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Corresponding Author

Wei Peng

Abstract

BackgroundAs one of the main causes of children's disability, cerebral palsy (hereinafter referred to as CP) affects the improvement of our population quality. At present, the results of researches on the prevalence of children suffering from CP in our country are quite different, and there is a lack of epidemiological studies based on larger sample sizes and the current prevalence of CP. ObjectiveTo learn about the prevalence of CP in children aged 0~6 years in China. MethodsLiteratures on the prevalence of CP in children aged 0~6 years in China were retrievaled through computer in PubMed, Web of Science, The Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service System, VIP Database (VIP), and China Biology Medicine disc(CBM), and the publication date limited from January 1st to January 1st, 2020. Based on established inclusion criteria, literatures were screened. Meta-analysis was performed on the included literatures with Stata 12.0 software, the prevalence was quantitatively combined, and subgroup analysis was carried out on classification indicators, such as gender and age. ResultsThis study finally included 8 papers of medium or above quality, with a total of 527,758 people, including 1,022 CP children.The results of meta-analysis proved that the overall prevalence of CP in children aged 0 to 6 in China was 0.23%〔95%CI(0.17%, 0.29%)〕. The subgroup analysis results revealed that the prevalence of boys was 0.22%〔95%CI(0.14%, 0.29%)〕, the prevalence of girls was 0.12%〔95%CI(0.06 %, 0.19%)〕. The prevalence of CP among children at the ages of below one years, one years, two years, three years, four years, five years, and six years was 0.21%〔95%CI(0.02%, 0.40%)〕, 0.20%〔95%CI(0.10%, 0.30%)〕, 0.19%〔95%CI(0.08%, 0.30%), 0.21%〔95%CI(0.09%, 0.32%)〕, 0.13%〔95%CI(0.02%, 0.24%)〕, 0.20%〔95%CI(0.09 %-0.32 %)〕, 0.32 %〔95%CI(0.14 %-0.50 %)〕, respectively. ConclusionThe prevalence of CP in children aged 0 to 6 in China was 0.23%, and the prevalence of gender and age was different, guiding significance for policy formulation and clinical intervention. It is recommended to conduct more cross-sectional investigations based on the new classification of CP.

Original Publcation Date of Chinese Version

2021-02-15

Original Issue

5

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