Corresponding Author

Hongying Bai


The research investigated the relationship between heart rate variability(HRV)and the distribution of EPVSs in the brain. The rMMSD had a negative correlation with BG-EPVS severity score and a positive correlation with the EPVS dominance model,and was independently associated with the BG-EPVS severity score and EPVS dominance model, suggesting that an imbalance in the autonomic nervous system induced by declined rMMSD may cause blood-brain barrier disruption or reduced metabolic waste clearance in the brain,which may play a role in the pathophysiological mechanism of BG-EPVS formation.